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Vanquish® Water Vapor Ablation System

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What Is Water Vapor Ablation?

Vanquish is a minimally invasive, transurethral treatment that uses water vapor (steam) to ablate targeted prostate tissue. A thin, needle-shaped catheter is deployed from the device and advanced to the targeted area, where short, precise bursts of steam destroy the tissue within the treatment zone. Additional steam may be delivered to the surrounding margin to help ensure full ablation of the targeted tissue.

Vanquish is performed through the urethra, so there are no incisions. The procedure is performed in an outpatient setting at an ambulatory surgery center (ASC) or hospital outpatient department, and most men go home the same day. Vanquish is designed to treat prostate tissue in a targeted way, which helps preserve surrounding healthy tissue and keeps other treatment options open for the future, if needed.

How Does Vanquish Water Vapor Ablation Work?

Vanquish works by delivering short bursts of steam to precisely ablate targeted prostate tissue. Here is what you can expect throughout the Vanquish treatment process.

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Consultation and Evaluation

Our staff will review your PSA levels, imaging, biopsy results, and overall health to determine whether Vanquish is an appropriate option for you and how it fits into your overall care plan.

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Pre-Procedure Planning

MRI images are typically used to develop your procedure plan and map the exact area of prostate tissue to be treated. Prior to and upon arrival for the procedure, prep will occur according to the facility protocol.
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The Vanquish Procedure

The procedure is performed under general anesthesia with antibiotics administered through an IV. A urinary drainage catheter is placed, and your physician uses the pre-procedure MRI images combined with live ultrasound to guide the Vanquish device through the urethra and deliver water vapor directly to the targeted tissue.
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Same-Day Discharge

Vanquish is an outpatient procedure. Recovery times vary, but most patients go home within 1-3 hours after the procedure once your physician determines you are ready for discharge.
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Short-Term Recovery

A catheter will stay in place for a few days after the procedure to help with healing and urination. Most side effects are minor and resolve within a few days, and patients report minimal impact on daily activities during recovery.
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Follow-Up and Monitoring

After the catheter is removed, your care team will continue to monitor your PSA levels and overall response through follow-up appointments. Vanquish is a tissue-preserving procedure, so options for additional prostate procedures remain open in the future if they are ever needed.

Who Is a Candidate for Water Vapor Ablation?

Vanquish is designed for men seeking a minimally invasive, outpatient option for the ablation of targeted prostate tissue. Your physician will determine whether Vanquish is appropriate based on your PSA levels, MRI findings, biopsy results, and overall health. Vanquish may be considered for men who:

Have been diagnosed with intermediate-risk prostate cancer and want a targeted, tissue-preserving treatment option

Are seeking a minimally invasive, outpatient alternative to more aggressive surgical or radiation-based treatments

Want to preserve the option for future prostate procedures, if they ever become necessary

Prefer a treatment with minimal impact on daily activities during recovery

Are looking for an MRI-guided, precise approach that treats targeted prostate tissue while preserving surrounding healthy tissue

Are looking for an MRI-guided, precise approach that treats targeted prostate tissue while preserving surrounding healthy tissue

Close-up of medical equipment including catheters and a Foley catheter balloon on a blue sterile field.
Man wearing jeans standing at a white urinal with blue mosaic tiled wall in a restroom.
Person in gray clothes holding lower abdomen sitting on toilet, indicating urinary or bladder discomfort.
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What Are the Side Effects of Vanquish?

Because Vanquish is a minimally invasive, transurethral procedure performed in an outpatient setting, most men experience a straightforward recovery. In the VAPOR 2 clinical study, the majority of patients reported no pain, and most side effects were minor and resolved within a few days. Below are the most common things to expect during recovery.
A urinary catheter remains in place for a few days after the procedure to help with healing and urination. Most men have the catheter removed at a short follow-up appointment.
As the prostate heals, some men experience temporary changes in urinary function, such as urgency, frequency, or mild irritation. These typically resolve within a few days.
Rates of urinary incontinence with Vanquish are minimal compared to more invasive prostate treatments.
Vanquish has been associated with low rates of erectile dysfunction in clinical study, in part because the procedure is designed to preserve surrounding healthy tissue.
Most side effects reported in clinical study were minor and resolved within a few days. Patients describe minimal impact on daily activities during recovery.
In the VAPOR 2 study at 12 months, 93% of patients were extremely satisfied or satisfied with the Vanquish procedure, and 94% believed the Vanquish procedure was a good decision (n=107).
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Is Vanquish® Right for You?

At Atlanta Prostate Center, our physicians review your imaging, PSA levels, and overall health to determine whether Vanquish is an appropriate option for you. Vanquish is a newer, tissue-preserving approach that can be a strong fit for men who want a minimally invasive alternative to more aggressive procedures.

The Vanquish Water Vapor Ablation System has been cleared as a tool for the thermal ablation of targeted prostate tissue via a transurethral approach. The FDA has not evaluated the Vanquish System for the treatment of any disease, including prostate cancer, or evaluated the Vanquish System for any long-term prostate cancer treatment outcomes.

Frequently Asked Questions About Water Vapor Ablation

Q What Is Vanquish Used For? 

A
Vanquish is a Water Vapor Ablation System cleared as a tool for the thermal ablation of targeted prostate tissue via a transurethral approach. The procedure uses short bursts of steam, delivered through a needle-shaped catheter, to ablate a defined area of prostate tissue while preserving surrounding healthy tissue. It is performed on an outpatient basis, so most men go home the same day.

Q How Does the Vanquish Procedure Work?

A
The Vanquish device is inserted into the urethra and advanced to the prostate. A small, needle-shaped catheter is then deployed from the device and moved to the targeted tissue. The physician uses MRI imaging combined with live ultrasound to deliver multiple short treatments of water vapor that destroy the tissue within the target location. Steam may also be delivered to the margin around the targeted tissue to help ensure full ablation.

Q How Long Is Recovery After Vanquish? 

A

Vanquish is an outpatient procedure, and most patients go home within 1-3 hours after the procedure once their physician clears them for discharge. A catheter remains in place for a few days to support healing, and most side effects resolve within a few days. Patients report minimal impact on daily activities during recovery, though your physician will give you specific guidance based on your individual care plan.

Q Is Vanquish Covered by Insurance or Medicare?

A
As a newer treatment option for the ablation of targeted prostate tissue, coverage and payment are still being established with insurance companies. Medicare covers procedures that are considered reasonable and medically necessary; however, health plans determine coverage and medical necessity on a case-by-case basis. We recommend obtaining prior authorization or predetermination when available, and our team can help you understand your options.