High Contrast Mode:

Pulsed Electrical Field (PEF) Ablation

A Revolutionary Treatment to Prostate Cancer Care

What is PEF Ablation?

Pulsed Electrical Field (PEF) ablation is a gentle, non-thermal treatment that uses short electrical pulses to target and destroy prostate cancer cells without heating or burning the tissue. During the procedure, a thin probe is placed directly into the area of the prostate where the cancer is located. The electrical pulses create tiny openings in the cancer cell walls, causing them to die while leaving the surrounding healthy tissue, nerves, and urinary structures unharmed. By precisely targeting only the cancerous tissue while preserving the surrounding healthy prostate, patients benefit from high accuracy, fewer side effects, and rapid recovery.

Prostate Cancer Facts
Medical professional performing a procedure with a needle on a patient in a clinical setting.
A doctor reviews a clipboard while consulting with a patient, stethoscope on the table.
Surgeons performing a delicate operation in a sterile environment with focus and precision.
Two men in business attire discussing work while looking at a laptop in a bright office setting

Your Treatment Journey

Advanced Planning

Before the procedure, each patient undergoes high-resolution imaging, including either multi-parametric MRI or PET-CT. These scans are used to precisely localize the cancer within the prostate and determine the extent and aggressiveness of the tumor.
Schedule Appointment

Surgical Intervention

Using a proprietary, image-guided surgical navigation system, a 3D map of the patient's prostate is created. This allows the physician to accurately visualize the location and boundaries of the tumor in real time. Plan and navigate the probe trajectory with sub-millimeter precision and maximize cancer control while preserving surrounding structures.
Schedule Appointment

Recovery

Patients return home the same day with minimal pain, controlled by Tylenol or Ibuprofen. Most patients go home urinating on their own and return to normal activities within 1-2 days.
Schedule Appointment

How PEF Works

The PEF procedure offers an exciting opportunity to revolutionize cancer care by triggering a systemic immune response that can target and control cancer beyond the localized treatment site.

Directly Destroys Cancer Cells: Pulsed Electrical Field (PEF) Ablation applies high-voltage electrical pulses to a cancer cell, causing irreversible damage to cell membranes and leading to cancer cell death at the treatment site.

Damaged Cancer Cells Release Antigens: The damaged cancer cells release cancer-specific antigens and other signals that are recognized by the immune system as a result of the treatment.

Immune System Activation: These released antigens and signals stimulate the immune system, activating it to target and attack cancer cells not just at the treatment site, but also in other areas of the body.

Systemic Immune Response: The activated immune system can now recognize and attack cancer cells elsewhere in the body, leading to the abscopal effect - the shrinkage or control of distant, untreated cancer.

Schedule Appointment
A medical device featuring a needle for precise applications in a sterile environment.

Why Consider PEF for Prostate Cancer?

Minimalist shield icon representing security and protection concepts.

Fewer Side Effects

Aims to reduce the risk of common side effects like incontinence and erectile dysfunction compared to whole-gland treatments.

Outline of a modern healthcare clinic featuring a cross symbol and a welcoming entrance.

Outpatient Procedure

Often performed in an Ambulatory Surgery Center (ASC) setting, allowing patients to return home the same day.

A minimalist black outline of a leaf symbolizing nature and growth.

Minimally Invasive

Typically performed through small probes, avoiding large incisions, leading to potentially faster recovery.

Black snowflake design with a central circle and intricate, radiating branches.

Tissue-Sparing Potential

Designed to protect vital structures like nerves responsible for erectile function and the sphincter muscle controlling continence.

Simple black target icon with an arrow hitting the bullseye, symbolizing success and precision.

Precise & Focused

Targets only the cancerous area (focal therapy), preserving the healthy parts of the prostate.

Universal no symbol featuring an exclamation mark within a circle, indicating caution or prohibition.

Non-Thermal

Avoids heat-related damage to adjacent tissues often seen with other ablation methods.

Receive Advanced Prostate Cancer Treatment

Discuss your diagnosis and treatment options with our specialists to see if PEF Ablation is the right choice for you.

Schedule An Appointment

Is PEF Right for You?

PEF is an innovative option, often best suited for men with localized prostate cancer (cancer confined to the prostate gland) that is visible on imaging like MRI. It is important to note that eligibility requires a thorough evaluation, including review of biopsy results, PSA levels, imaging, and overall health.

Ideal candidates typically have the following:

  • Cancers identifiable via MRI or advanced ultrasound.
  • Desire to minimize side effects and preserve urinary and sexual function.
  • Interest in focal therapy (treating only the cancer) rather than the whole prostate gland.

Why Choose Advanced Urology for PEF?

Advanced Urology is one of the best prostate cancer treatment centers because we are committed to offering the most advanced and effective treatments. Our team includes experts highly skilled in performing PEF ablation. We bring unmatched experience and innovation to every case, such as:

  • Pioneering Expertise: We are proud to be the first Ambulatory Surgical Center (ASC) in the world to perform PEF for prostate cancer.
  • Specialized Training: Our physicians have undergone specific training for this technology.
  • State-of-the-Art Facility: Utilizing the latest imaging and PEF equipment.
  • Patient-Centered Care: Focused on personalized treatment plans and maximizing quality of life.
Schedule Appointment
a man and a woman smiling